abstract：:Experimentalallergic encephalomyelitis (EAE) is an animal model for inflammatory demyelinating autoimmune disease, i.e., multiple sclerosis (MS). In the present study, we investigated the antineuroinflammatory/neuroprotective effects of C16, an ανβ3 integrin-binding peptide, and recombinant rat ciliary neurotrophic fa...

journal_title：Frontiers in neuroanatomy

authors： Fang M,He D,Zhang F,Hu Z,Yang J,Jiang H,Han S

更新日期：2013-12-30 00:00:00

abstract：:Over the last 60 years, the spotlight of research has periodically returned to the cerebellum as new techniques and insights have emerged. Because of its simple homogeneous structure, limited diversity of cell types and characteristic behavioral pathologies, the cerebellum is a natural home for studies of cell specifi...

journal_title：Frontiers in neuroanatomy

authors： Basson MA,Wingate RJ

更新日期：2013-09-03 00:00:00

abstract：:Ketamine, a known antagonist of N-methyl-D-aspartic (NMDA) glutamate receptors, had been used as an anesthetic particularly for pediatric or for cardiac patients. Unfortunately, ketamine has become an abusive drug in many parts of the world while chronic and prolonged usage led to damages of many organs including the ...

journal_title：Frontiers in neuroanatomy

authors： Wang C,Zheng D,Xu J,Lam W,Yew DT

更新日期：2013-07-17 00:00:00

abstract：:Historically, the molecular and cellular mechanisms of cerebellar development were investigated through structural descriptions and studying spontaneous mutations in animal models and humans. Advances in experimental embryology, genetic engineering, and neuroimaging techniques render today the possibility to approach ...

journal_title：Frontiers in neuroanatomy

authors： Martinez S,Andreu A,Mecklenburg N,Echevarria D

更新日期：2013-06-26 00:00:00

abstract：:This study presents a tool, Neuronize, for building realistic three-dimensional models of neuronal cells from the morphological information extracted through computer-aided tracing applications. Neuronize consists of a set of methods designed to build 3D neural meshes that approximate the cell membrane at different re...

journal_title：Frontiers in neuroanatomy

authors： Brito JP,Mata S,Bayona S,Pastor L,Defelipe J,Benavides-Piccione R

更新日期：2013-06-03 00:00:00

abstract：:Embryonic development in mammals has evolved a platform for genomic conflict between mothers and embryos and, by extension, between maternal and paternal genomes. The evolutionary interests of the mother and embryo may be maximized through the promotion of sex-chromosome genes and imprinted alleles, resulting in the r...

journal_title：Frontiers in neuroanatomy

authors： Lewitus E,Kalinka AT

更新日期：2013-04-09 00:00:00

abstract：:The recent concept of neural genoarchitecture (or genoarchitectonics) is examined from several angles, aiming to clarify the rationale for this new approach in causal and descriptive neuroanatomy. Gene expression patterns can be used as topographic stains revealing architectonic borders that may clarify, dispute, or c...

journal_title：Frontiers in neuroanatomy

authors： Puelles L,Ferran JL

更新日期：2012-11-16 00:00:00

abstract：:In rodents, sexual behavior depends on the adequate detection of sexually relevant stimuli. The olfactory bulb (OB) is a region of the adult mammalian brain undergoing constant cell renewal by continuous integration of new granular and periglomerular neurons in the accessory (AOB) and main (MOB) olfactory bulbs. The p...

journal_title：Frontiers in neuroanatomy

authors： Portillo W,Unda N,Camacho FJ,Sánchez M,Corona R,Arzate DM,Díaz NF,Paredes RG

更新日期：2012-07-06 00:00:00

abstract：:Until recently it was widely believed that the ability of female mammals (with the likely exception of women) to identify and seek out a male breeding partner relied on the detection of non-volatile male pheromones by the female's vomeronasal organ (VNO) and their subsequent processing by a neural circuit that include...

journal_title：Frontiers in neuroanatomy

authors： Baum MJ

更新日期：2012-06-05 00:00:00

abstract：:Larger mammalian cerebral cortices tend to have increasingly folded surfaces, often considered to result from the lateral expansion of the gray matter (GM), which, in a volume constrained by the cranium, causes mechanical compression that is relieved by inward folding of the white matter (WM), or to result from differ...

journal_title：Frontiers in neuroanatomy

authors： Mota B,Herculano-Houzel S

更新日期：2012-02-02 00:00:00

abstract：:The study of the links and interactions between development and motor learning has noticeable implications for the understanding and management of neurodevelopmental disorders. This is particularly relevant for the cerebellum which is critical for sensorimotor learning. The olivocerebellar pathway is a key pathway con...

journal_title：Frontiers in neuroanatomy

authors： Manto MU,Jissendi P

更新日期：2012-01-23 00:00:00

abstract：:Drug addiction is a severe neuropsychiatric disorder characterized by loss of control over motivated behavior. The need for effective treatments mandates a greater understanding of the causes and identification of new therapeutic targets for drug development. Drugs of abuse subjugate normal reward-related behavior to ...

journal_title：Frontiers in neuroanatomy

authors： Philibin SD,Hernandez A,Self DW,Bibb JA

更新日期：2011-09-20 00:00:00

abstract：:Huntington's Disease (HD) is the most frequent neurodegenerative disease caused by an expansion of polyglutamines (CAG). The main clinical manifestations of HD are chorea, cognitive impairment, and psychiatric disorders. The transmission of HD is autosomal dominant with a complete penetrance. HD has a single genetic c...

journal_title：Frontiers in neuroanatomy

authors： Roze E,Cahill E,Martin E,Bonnet C,Vanhoutte P,Betuing S,Caboche J

更新日期：2011-08-23 00:00:00

abstract：:Pyramidal cells grow and mature at different rates among different cortical areas in the macaque monkey. In particular, differences across the areas have been reported in both the timing and magnitude of growth, branching, spinogenesis, and pruning in the basal dendritic trees of cells in layer III. Presently availabl...

journal_title：Frontiers in neuroanatomy

authors： Elston GN,Oga T,Okamoto T,Fujita I

更新日期：2011-07-21 00:00:00

abstract：:Birds use various vocalizations to communicate with one another, and some are acquired through learning. So far, three families of birds (songbirds, parrots, and hummingbirds) have been identified as having vocal learning ability. Previously, we found that cadherins, a large family of cell-adhesion molecules, show voc...

journal_title：Frontiers in neuroanatomy

authors： Matsunaga E,Okanoya K

更新日期：2011-04-20 00:00:00

abstract：:The development of the mammalian neocortex relies heavily on subplate. The proportion of this cell population varies considerably in different mammalian species. Subplate is almost undetectable in marsupials, forms a thin, but distinct layer in mouse and rat, a larger layer in carnivores and big-brained mammals as pig...

journal_title：Frontiers in neuroanatomy

authors： Montiel JF,Wang WZ,Oeschger FM,Hoerder-Suabedissen A,Tung WL,García-Moreno F,Holm IE,Villalón A,Molnár Z

更新日期：2011-04-07 00:00:00

abstract：:Species-typical patterns of grouping have profound impacts on many aspects of physiology and behavior. However, prior to our recent studies in estrildid finches, neural mechanisms that titrate species-typical group-size preferences, independent of other aspects of social organization (e.g., mating system and parental ...

journal_title：Frontiers in neuroanatomy

authors： Goodson JL,Kingsbury MA

更新日期：2011-03-02 00:00:00

abstract：:Hippocampal sclerosis is the most frequent pathology encountered in resected mesial temporal structures from patients with intractable temporal lobe epilepsy (TLE). Here, we have used stereological methods to compare the overall density of synapses and neurons between non-sclerotic and sclerotic hippocampal tissue obt...

journal_title：Frontiers in neuroanatomy

authors： Alonso-Nanclares L,Kastanauskaite A,Rodriguez JR,Gonzalez-Soriano J,Defelipe J

更新日期：2011-02-24 00:00:00

abstract：:The mammalian oculomotor nucleus receives a strong γ-aminobutyric acid (GABA)ergic synaptic input, whereas such projections have rarely been reported in fish. In order to determine whether this synaptic organization is preserved across vertebrates, we investigated the GABAergic projections to the oculomotor nucleus in...

journal_title：Frontiers in neuroanatomy

authors： Luque MA,Torres-Torrelo J,Carrascal L,Torres B,Herrero L

更新日期：2011-02-04 00:00:00

abstract：:Striatal dopamine (DA) denervation results in a significant loss of dendritic spines on medium spiny projection neurons in Parkinson's disease. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated parkinsonian monkeys, spines contacted either by cortical or thalamic glutamatergic terminals are severely affected on ...

journal_title：Frontiers in neuroanatomy

authors： Villalba RM,Smith Y

更新日期：2010-12-10 00:00:00

abstract：:Involuntary movements or dyskinesia, represent a debilitating complication of levodopa therapy for Parkinson's disease. Dyskinesia is, ultimately, experienced by the vast majority of the patients. Despite the importance of this problem, little was known about the cause of dyskinesia, a situation that has dramatically ...

journal_title：Frontiers in neuroanatomy

authors： Barroso-Chinea P,Bezard E

更新日期：2010-09-14 00:00:00

abstract：:Subsets of GABAergic neurons are able to maintain high frequency discharge patterns, which requires efficient replenishment of the releasable pool of GABA. Although glutamine is considered a preferred precursor of GABA, the identity of transporters involved in glutamine uptake by GABAergic neurons remains elusive. Mol...

journal_title：Frontiers in neuroanatomy

authors： Solbu TT,Bjørkmo M,Berghuis P,Harkany T,Chaudhry FA

更新日期：2010-02-08 00:00:00

abstract：:The white matter (WM) of the adult human neocortex contains the so-called "interstitial neurons". They are most numerous in the superficial WM underlying the cortical gyri, and decrease in density toward the deep WM. They are morphologically heterogeneous. A subgroup of interstitial neurons display pyramidal-cell like...

journal_title：Frontiers in neuroanatomy

authors： Suárez-Solá ML,González-Delgado FJ,Pueyo-Morlans M,Medina-Bolívar OC,Hernández-Acosta NC,González-Gómez M,Meyer G

更新日期：2009-06-09 00:00:00

abstract：:Dual transneuronal tracing is a novel viral tracing methodology which employs two recombinant viruses, each expressing a different reporter protein. Peripheral injection of recombinant pseudorabies viruses has been used as a powerful method to define neurons that coordinate outputs to various peripheral targets of mot...

journal_title：Frontiers in neuroanatomy

authors： Ohara S,Inoue K,Yamada M,Yamawaki T,Koganezawa N,Tsutsui K,Witter MP,Iijima T

更新日期：2009-01-19 00:00:00

abstract：:We evaluated the neuropil distribution of the enzymes NADPH diaphorase (NADPH-d) and cytochrome oxidase (CO) in the spinal cord of the agouti, a medium-sized diurnal rodent, together with the distribution pattern and morphometrical characteristics of NADPH-d reactive neurons across different spinal segments. Neuropil ...

journal_title：Frontiers in neuroanatomy

authors： Freire MA,Tourinho SC,Guimarães JS,Oliveira JL,Picanço-Diniz CW,Gomes-Leal W,Pereira A

更新日期：2008-05-26 00:00:00